Spira Health is medical device start-up with a mission to provide evidence-based and ease-to-use consumer-facing solutions for sleep disorders.

My responsibilities as the Research Lead include:

• Lead clinical evidence research and market research.
• Conduct medical literature research, develop research surveys, and perform statistical analyses.
• Oversee financial aspects of the company, including bookkeeping and generating financial statement.
• Lead the development of a mobile app for a breath training device for sleep disorders.

Conduct innovative research using large administrative data. Research projects include:

• Develop and evaluate a predictive model for hospital re-admission due to prosthetic joint infection after primary joint replacement for osteoarthritis.
• Conduct individual patient meta-analysis using clinical trial data to evaluate vitamin D supplementation for osteoarthritis.
• Conduct causal inference studies using the target trial framework to evaluate non-surgical interventions for osteoarthritis.

Conduct clinical research to discover optimal weight loss interventions to prevent osteoarthritis in people with obesity. Research projects include:

• Identify and validate osteoarthritis biomarkers to be used in clinical trials.
• Evaluate the effects of weight loss on the changes in osteoarthritis biomarkers.
• Develop self-management interventions for patients with obesity and osteoarthritis.

Lead a clinical trial to evaluate a behavior intervention for smoking relapse among ex-prisoners. Responsibilities include:

• Manage a team of five associates and coordinate day-to-day trial operations, including participant recruitment and follow-up.
• Perform sample size calculation, develop randomization strategy, conduct statistical analysis, generate dynamic reports and produce manuscript for publication.
• Develop trial documents, including SOP, SAP, DMP, informed consent and research questionnaires.

Evaluate the impacts of an electronic medication management system on medication errors. Responsibilities include:

• Develop electronic tool for capturing prescribing error during medication record review.
• Medication data management and data cleaning for analysis.
• Prepare dynamic data summary reports and preliminary statistical analysis reports.

Zong Qi Se Medicine is pharmaceutical company of traditional Chinese medicine for chronic diseases. Responsibilities include:

• Provide medical advice and technical information on new and existing products.
• Conduct literature search and review, and disseminate information for sales/marketing/R&D.
• Provide medical writing supports and generate sales and marketing promotional materials.

The First People Hospital of Chengdu City is a tertiary teaching hospital. Responsibilities include:

• Perform clinical tasks with consultation from registrars or specialist consultants.
• Communicate with patients and family about diagnosis and treatment plan.
• Clinical rotations in Obstetrics, Gynecology and Emergency Department.